Such a tremendous amount of research and development is involved in bringing a new vaccine to market, that we tend to forget about all of the other moving pieces in the process. Distributing these vaccines is one such overlooked area that can be critically important. This is especially true when a vaccine has stringent storage requirements. Such is the case with mRNA vaccines, several of which have been developed to protect against infection from COVID-19. Current COVID-19 vaccines require ultra-low temperature storage, in the range of -86° C to -45° C; any exposure to warmer temperatures can render the vaccines ineffective.
This is a companion discussion topic for the original entry at https://www.edgeimpulse.com/blog/maybe-its-cold-inside